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However, systematic toxicological characterization remains uneven: many ethnopharmacological reports do not include rigorous cytotoxicity screening, concentrationresponse data, or physiologically relevant models (Anywar et al., 2022)

Dacomitinib, an EGFR inhibitor, reduces tumor viability and self-renewal in EGFR-amplified GBM, although its effectiveness is influenced by the PTEN status, 383,384 Despite their initial promise, c-MET inhibitors such as onartuzumab and rilotumumab have failed to significantly improve survival outcomes

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There have been no official reports of interactions between glutathione and other supplements/medications

Protein carbonyl assay A protein carbonyl colorimetric assay kit (Cayman chemical) was used to assay the carbonyl content in human and mouse brains or hearts