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However, cardiac expression of the nicotinamide phosphoribosyl transferase (NAMPT) is also almost systematically repressed in HF models and could lead to deficient NAD biosynthesis [185,186]

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It stimulates the breakdown of fat (lipolysis) and inhibits the process by which the body stores fat (lipogenesis)

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Severe, long-term deficiency may lead to loss of mobility, problems walking, or memory loss