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Krekels EH, Danhof M, Tibboel D et al , Ontogeny of hepatic glucuronidation

10.1016/0267-6605(94)90116-3 7 AltschulerS

J Chromatogr B Anal Technol Biomed Life Sci 964:191194

CASP4/caspase-11 Promotes Autophagosome Formation in Response to Bacterial Infection

Liver Disease Advanced liver fibrosis or cirrhosis [54] in HFE-related hemochromatosis is rare under the age of 45 years in the absence of other liver co-morbidities, occurring in 825% of all HFE p.Cys282Tyr homozygotes [38, 51, 52, 55, 56]

The limited success of current therapies is largely due to the poor bioavailability of pharmacologically active agents in the brain, primarily due to the restrictive nature of the BBB