what is the primary function of glutathione in the body Master Antioxidant? Here’s Science Says What Is Glutathione? Benefits, Uses

Clinical Chemistry & Laboratory Medicine 2005;43:11649

Belous AR, Hachey DL, Dawling S, Roodi N, Parl FF

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Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases

The consequences of Nrf2 impairment in CF include weakened intrinsic antioxidant defense capacity and increased intracellular H 2 O 2 levels, which contribute to the overproduction of pro-inflammatory cytokines like IL-6 and IL-8, directly linking defective antioxidant response to CFs characteristic chronic inflammation (Chen et al., 2008)