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Statistics estimate that approximately 1% of the global population suffers from RA, and the incidence rate of RA in women is three to four times higher than that in men (4, 5)

As a result, various industries, including food, pharmaceutical, cosmetic, and agricultural, have found valuable uses for CBS due to its nutritious content

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By directly testing whether activated neurons primarily oxidize astrocyte-derived lactate versus other substrates, and by accurately accounting for all sources of oxygen (vascular and extravascular), such approaches could provide definitive evidence to reconcile the conflicting models (Tietze, 1969

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