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The review protocol was registered on PROSPERO (Registration ID: CRD42025644894), ensuring methodological transparency and adherence to systematic review guidelines

The biggest risk is the lack of safety evidence

They bind to GLP-1 receptors throughout the body and produce a prolonged version of the natural response, dramatically reducing hunger, improving insulin sensitivity, and driving significant weight loss

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Because both disorders may co-exist, neurologists should be familiar with their phenomenology and clinical features to differentiate them and provide appropriate treatments