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10.1074/jbc.272.30.18515 29 GaoZ.SarsourE

Although IGF-1 can stimulate neurogenesis and promote cognition in short-term, some studies have demonstrated that chronic administration of IGF-1 causes side effects such as accelerated aging, cancer development, and decreased lifespan [80, 81]

Like in ferroptosis, erythrocytes frequently experience ROS overgeneration and depletion of GSH and antioxidant enzymes in response to xenobiotics [220]

This stress reduces the energy produced and stored in cells, causing damage and affecting their ability to work properly

Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis