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Los primeros experimentos en animales llevados por Whipple, en la dcada de los aos 20 del siglo XX, sobre enzimas hepticas, enfermedad heptica y hemoglobina, demostraron que la ingesta de hgado y de sus extractos mejoraba los cuadros de anemia convencional, lo que sirvi para abrir una va de investigacin para la anemia perniciosa, todava un gran misterio

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2.2 Anatomical and functional framework of the cerebellum in pain The cerebellum constitutes only a small fraction of total brain volume, yet it contains more than half of all neurons in the central nervous system (27, 30)