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doi: 10.1002/ueg2.12636 37 FangZ.YangX.ShangL

Notably, mitochondrial dynamics proteins, particularly Drp1-mediated fission and OPA1-regulated membrane remodeling, have been increasingly implicated in facilitating the cytosolic release and subsequent EV-packaging of mtDNA, suggesting a mechanistic crosstalk between mitochondrial dynamics and EV-mediated mitochondrial cargo transfer [425]