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In that ( final rule, we also described that CRC screening presents a unique scenario where there are significant differences between screening stool-based tests and screening colonoscopy tests in terms of invasiveness and burdens to the patient and healthcare system

doi: 10.1016/j.canlet.2018.08.002 126 WangSZhangZQianWJiDWangQJiBet al

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Mutating its signal peptide to accelerate its cleavage alters the timing of gp160 oxidation, the final conformation of the gp160 protein, and ultimately the relative fitness of the virus (Snapp et al., 2017)

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