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Certain oral bacteria are potent inducers of pro-inflammatory cytokines and have been significantly linked to the onset of hypertension 67

This observation suggests that PG is natively present in Lgt, as revealed by the crystal structure, and that prior binding of the acceptor prolipoprotein substrate is not required for the binding of the donor-substrate PG

[PubMed: 10964930] 698

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It consists of the amino acid sequence from positions 176 to 191, located at the C-terminus of the parent hormone

3) and the absence of any renal drug transporters contributing to renal excretion as suggested from the in vitro study, indicates that, more specifically, elimination of pudexacianinium can be explained almost entirely by glomerular filtration