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Lipid peroxidation and autophagy are closely linked processes, where lipid peroxidation can trigger autophagic responses, and autophagy regulates lipid peroxidation to maintain cellular homeostasis (Fig

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Furthermore, it has been suggested that cell damage may result in high plasma glutamine, due to leakage of intracellular glutamine from the destroyed cells into plasma [10], as intracellular glutamine concentrations greatly exceed plasma concentration in many tissues [25,26,27,28]