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Plasma glial fibrillary acidic protein is associated with 18F-SMBT-1 PET: two putative astrocyte reactivity biomarkers for Alzheimers disease

Some individuals may struggle to absorb enough B12 from their diet, especially those with conditions like pernicious anemia, certain gastrointestinal disorders, or those taking medications that impact absorption

There are also reports of ebselen conjugates with commonly used drugs, such as clioquinol, a compound known for its ability to chelate metal ions and inhibit A deposition

J.MaedaJ.et al

The antibodies prevent the B12 from binding to the intrinsic factor resulting in a deficiency

Mutat Res 590(13):1280