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DNA region enriched in hypo-methylation can increase expression of some of the affected genes [10,35,56]

The supplement requires the company to update its labeling to include the risk of thrombotic microangiopathy, in which blood clots may form in blood vessels, restricting blood flow and causing organ damage

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Future research should prioritize strategies that modulate GAM polarization, suppress MDSCs, and reinvigorate exhausted T cells to strengthen antitumor immunity and improve therapeutic outcomes

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