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521 Elevated hepatic insulin/AKT signaling supports liver regeneration by driving the synthesis of proteins, lipids, and glycogen

doi:10.1007/s11886-023-01992-6

These cells secrete various proinflammatory mediators such as cytokines, chemokines, growth factors, and lipid mediators

The basis of the pathological change is the cells inability to prevent protein misfolding, to revert misfolded proteins to normal, or to eliminate misfolded proteins by degradation