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This molecular remodeling of the BBB facilitates the transmigration of peripheral immune cells, including T lymphocytes and monocytes/macrophages, across the vascular barrier and their subsequent infiltration into the CNS parenchyma (53, 54)

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PSP is caused by damage to nerve cells in areas of the brain that control thinking and body movements

Cancer treatments such as chemotherapy and radiation can impact the nervous system and cause unusual pain signals

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