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NICE NG28 (Type 2 Diabetes in Adults: Management) and associated NICE pathways highlight that HbA1c results should be interpreted in the context of the patient's full clinical picture

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In subjects with inadequate testosterone production or action, if adequate androgen imprinting has not occurred, the sex of rearing may become the predominant factor

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For instance, glutathione peroxidase 4 (GPX4), a core regulatory gene involved in ferroptosis, is negatively associated with the prognosis of breast cancer, as its expression enhances ferroptosis in cells (9)