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Furthermore, impaired clearance of apoptotic cells leads to the secretion of anti-nuclear antibodies from auto-reactive B cells

Although many studies reveal associations between platelet biomarkers and ASD, there is an important knowledge gap in linking these markers with ASD and explaining the altered platelet phenotypes detected in ASD patients [406]

10.1111/j.1742-4658.2010.07754.x 82 Rabinovich-NikitinI.KirshenbaumE.KirshenbaumL

Expert Opinion on Therapeutic Patents

None of these studies however specifically encompasses the domain of brain cancer therefore the huge gap in translational studies of Nrf2 modulators on brain cancer is evident, even though the opportunity for exploration is heavily backed by pre-clinical findings