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Los steres de cidos grasos (de la CoA) se forman casi exclusivamente en el citosol y no se transportan a travs de la membrana, inhibe tambin enzimas de ciclo de Krebs, por ende la oxidacin de cidos grasos requiere la formacin de acilcarnitinas y su translocacin hacia las mitocondrias, donde se vuelven a formar steres de CoA y se metabolizan produciendo energa