It is known to induce CYP3A4 and CYP2C8/9 enzymes, starting within 4 days of the first dose and returning to baseline 14 days after discontinuation
L-ascorbic acid requires a low pH (typically below 3.5) to remain stable, and that acidic environment can disrupt the copper complex in GHK-Cu, potentially degrading both ingredients
All stability samples were qualified by the result that there were no significant difference compared to the result in precision (Table 1)
doi: 10.1055/s-2007-1024611
C., Cheetham, T
WATER, NIACINAMIDE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, GLUTATHIONE, CETEARYL OLIVATE, POLYACRYLAMIDE, SORBITAN OLIVATE, 1,2-HEXANEDIOL, C13-14 ISOPARAFFIN, PULSATILLA KOREANA EXTRACT, USNEA BARBATA (LICHEN) EXTRACT, ZANTHOXYLUM PIPERITUM FRUIT EXTRACT, CARBOMER, SODIUM HYALURONATE, TRIETHANOLAMINE, FRAGRANCE, GLYCERIN, LAURETH-7, BUTYLENE GLYCOL, LIMONENE, HEXYL CINNAMAL, LINALOOL, ETHYLHEXYLGLYCERIN, ACHILLEA MILLEFOLIUM EXTRACT, MALVA SYLVESTRIS (MALLOW) EXTRACT, MELISSA OFFICINALIS LEAF EXTRACT, MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT, PRIMULA VERIS EXTRACT, VERONICA OFFICINALIS EXTRACT, HYDROGENATED LECITHIN, GERANIOL, HAMAMELIS VIRGINIANA (WITCH HAZEL) LEAF EXTRACT, MORUS ALBA BARK EXTRACT, PHYLLANTHUS EMBLICA FRUIT EXTRACT, TRICHOSANTHES KIRILOWII ROOT EXTRACT, POLYGLYCERYL-10 STEARATE, BENZYL BENZOATE, PANTHENOL, SODIUM ASCORBYL PHOSPHATE, TOCOPHERYL ACETATE, GLYCERYL ARACHIDONATE, GLYCERYL LINOLENATE, ACETYL HEXAPEPTIDE-8, BIOTIN, FOLIC ACID, PYRIDOXINE, RETINYL PALMITATE, THIAMINE HCL, COPPER TRIPEPTIDE-1, OLIGOPEPTIDE-29, CYANOCOBALAMIN, OLIGOPEPTIDE-32, PALMITOYL PENTAPEPTIDE-4
