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Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15: Cell Reports Restoring Systemic GDF11 Levels Reverses Age Related Dysfunction in Mouse Skeletal Muscle Science Frontiers The GDF11 Promotes Nerve Regeneration After Sciatic Nerve Injury in Adult Rats by Promoting Axon Growth and Inhibiting Neuronal Apoptosis The versatility and paradox of GDF 11 ScienceDirect GDF11 and aging biology controversies resolved and pending Rather than a rejuvenating agent, GDF11 may have a detrimental effect on liver senescence. Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy [2021, open access] : r longevity
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