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Intraoperatively, he developed refractory vasoplegia despite high-dose norepinephrine, epinephrine, vasopressin, and phenylephrine therapy

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Needless to say, I wouldn't ignore it at this stage but I would look for an explanation

in this study no deamidation on N 393 was observed

Cycle Guidelines Approach Standard Duration 4-6 weeks Review point Week 4 Best for General research planning Approach Extended Duration 6-8 weeks Review point Week 6 Best for Stubborn-injury research models Approach Long Duration 8-12 weeks Review point Week 8 Best for Slow-remodeling tissue research planning Off periods of 2-4 weeks between cycles are common in research planning