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The nitrogen-containing compounds are broken down into amino acids and peptides and related enzymes are excreted via the exocrine pancreas

Exposure of aSyn to nitrating agents can encourage o,o-dityrosine crosslinking between the N-domain tyrosine (Y39) and C-terminal tyrosines (Y125, Y133, Y136) to generate aSyn-dimers that are more prone to oligomer formation 105,106,107,108

Trans fats raise cholesterol levels even more than saturated fats and are considered a risk factor for heart disease

They highlight that obesity can lead to the development of cardiovascular disease and potentially fatal events, independently of other cardiovascular risk factors

10 mmol/l final concentration) in phosphate buffer (pH 7.0) as the substrate

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