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These genuinely matter: Temperature matters: Sperm production is optimised at about 2C below body temperature hence the external location of the testes

J Model Manag 13(2):351374 Sarkar B, Moon I (2011) An EPQ model with inflation in an imperfect production system

Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial

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[DOI] [PubMed] [Google Scholar] 82.Kunwar A., Barik A., Mishra B., Rathinasamy K., Pandey R., Priyadarsini K.I

Symptoms may include: In cases of high creatinine due to medication toxicity: If a kidney infection (pyelonephritis) develops and treatment is neglected, the following symptoms may occur: In cases of glomerulonephritis, the symptoms associated with high creatinine may include: In cases of kidney failure, symptoms may include: Similar symptoms may also arise in conditions that can lead to kidney function impairment, such as high blood pressure, urinary tract obstruction, and heart disease