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Treatment of apigenin on vaginal mucosa-derived epithelial endometriotic cells (VK2/E6E7) and endocervix-derived endometriotic cells (End1/E6E7) cells resulted in the loss of mitochondrial membrane potential, increased calcium in the cytoplasm, elevated the expression of the pro-apoptotic protein Bax, and the release of cytochrome c (Cyt c)

However, to eliminate the AFM1 in animal products, increasing public awareness and regular monitoring of dairy products can be helpful (130)

The Ca 2+ /CaM-dependent phosphatase calcineurin is associated with the PMCA-eNOS complex, suggesting a potential role in the effect of PMCA expression on Thr495 phosphorylation status (Holton et al., 2010)