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Commonly used markers such as p16^INK4a, SA--galactosidase, and SASP cytokines (eg, IL-6, IL-8) show promise in experimental models but have variable sensitivity and specificity across tissues and disease contexts.1 Their expression can be transient, context-dependent, and influenced by non-senescent cellular states, complicating interpretation in human studies

World J Gastroenterol (2008) 14:5990

B-5 (D-Pantothenol) The stable form of pantothenic acid is involved in a number of biological reactions, including the production of energy, the synthesis of heme and acetylcholine, and the catabolism and synthesis of fatty acids, phospholipids, steroid hormones, and amino acids