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Most people tolerate this dose with minimal or no side effects

Salvatori S, Marafini I, Laudisi F, Monteleone G, Stolfi C (2023) Helicobacter pylori and gastric cancer: pathogenetic mechanisms

For instance, aspirin decreased pyloric sphincter pressure (23), while indomethacin was variously shown to have increased lower esophageal sphincter (18, 20, 22), decreased (19, 21) or had no effect (23) on lower esophageal sphincter pressure