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LAMPs were originally believed just to be structural proteins that protect lysosomal membrane from resident hydrolytic enzymes, although evidence now reveals that they have a key physiological role in suppressing proton leak through TMEM175 channels to facilitate re-acidification when lysosomal pH rises inappropriately 96

Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons

Cumulative incidence risk of HCC and assessment of its risk factors in AIH were estimated with competing risk analysis, regarding death and liver transplantation as competing risk for HCC

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Neuroscience 278 , 7080 (2014)