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RNA sequencing studies of fracture hematoma, ischemic penumbra, and peri-infarct tissue consistently demonstrate coordinated changes in Wnt/-catenin, BMP, mTOR, and NF-B signaling pathways

DOI:10.1002/14651858.CD005228.pub4 [ Links ] 66

In this model system, when we performed cytotoxicity assays in the presence or absence of 10 M valspodar, a P-gp inhibitor, we observed that P-gp overexpression conferred resistance to imidazole ketone erastin, piperazine erastin, and FIN56, and that valspodar reversed the resistance