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Aggregated -syn inhibits dopaminergic neurotransmission and reduces dopamine transporter levels

DOI: 10.1016/j.clnu.2014.05.006 Notes From Leguina-Ruzzi [16]

Our data showed a gradual increase in the mean values of comet tail length, tail moment, and percentages of DNA cleavage in HL-60 cells with increasing concentrations of GE, indicating that GE treatment is able to induce DNA damage in human leukemia cells in a concentration-dependent manner