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However, observational data and mechanistic reasoning suggest additive glucose-lowering effects without major pharmacokinetic interactions

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Cells 33 , 235241 (2012)

Gao JG, Yu MS, Zhang MM, Gu XW, Ren Y, Zhou XX, et al

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Methylation drives SLC2A1 transcription and ferroptosis process decreasing autophagy pressure in colon cancer

Ruan GX, Kazlauskas A (2013) Lactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis