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Unfortunately, many people struggle to get enough of these nutrients through diet and supplements alone

Global players such as Pfizer, AstraZeneca, and Novo Nordisk are partnering aggressively, reflecting decades of government investment in R&D infrastructure, streamlined approval pathways, and policies favouring data exclusivity

From here, GDP-D-mannose is converted to L-gulose in three reactions catalyzed by GDP-D-mannose3, 5-epimerase, GDP-L-gulose-1-P-phosphatase and L-gulose-1-P-phosphatase, respectively

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