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90 MazzottaA

doi:10.1093/ehjcvp/pvac054

Circulating mutant DNA to assess tumor dynamics

Publisher's Note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In the unaffected colonic mucosa of colorectal cancer patients, although the frequencies of T cells and tissue-resident memory T cells are decreased, the B cell memory response to commensal bacteria is significantly enhanced, accompanied by an increased proportion of effector memory B cells, transitional B cells, and plasma cells in peripheral blood [49]