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SKU: 2153446824
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G., Tripathi, Y

10.1109/JSEN.2021.3073974 87

505 Several pharmacological treatments have been employed in the therapeutic approach for cachexia among patients with HNC

Increased uptake of BCKAs by M1 macrophages inhibits the phagocytic capacity of M1 macrophages and may therefore produce immunosuppression

The above evidence converges to support the hypothesis that metabolic dysregulation, characterized by impaired glycolysis and PDH dysfunction, underlies the mitochondrial dysfunction observed in ME/CFS