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A small area of redness, mild swelling, warmth, and itch that peaks within 24 to 72 hours and then fades, sometimes helped by simple measures like a cold compress or topical soothing creams

This means that hydroxycobalamin stays in the body for longer periods of time and can provide sustained levels of vitamin B12, which may be beneficial for individuals with severe or chronic vitamin B12 deficiency

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However, neurological symptoms typically lag behind haematological improvement

While these rapid responses occur legitimately, they should not create unrealistic expectations

PMID 31193945