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We observed significant alterations in ferroptosis-related gene expression following combined treatment with A oligomers and GSH depletion

Oxid Med Cell Longev 2017:5601593 Mohd Isa IL, Teoh SL, Mohd Nor NH, Mokhtar SA (2022) Discogenic low back pain: anatomy, pathophysiology and treatments of intervertebral disc degeneration

More help This AOP was last modified on November 28, 2025 09:07 Revision dates for related pages Abstract A concise and informative summation of the AOP under development that can stand-alone from the AOP page

In human embryonic stem cells (hESCs), the conserved lncRNA-FAST binds to the WD40 domain of the E3 ubiquitin ligase -TrCP, inhibiting the ubiquitination of -catenin by -TrCP, resulting in the accumulation of -catenin in the nucleus

Drug triggered cutaneous neoplasia

Consequently, VBIT-4 attenuated the LPS/IFN--stimulated increases in iNOS, CD80, and CD86 protein expression and iNOS , IL-6 , and IL-1 mRNA expression, indicating that mtDNA released via VDAC1 oligomers contributes to macrophage polarization (Fig