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Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohns disease recurrence

Neural precursor cell expressed, developmentally downregulated 9 (NEDD9), a scaffolding protein associated with poor prognosis in multiple cancers, shows significantly elevated expression in hepatocellular carcinoma (HCC) tissues versus adjacent non-tumor liver (84)

I discuss how dreams during rapid eye movement (REM) sleep contribute to emotional learning and the processing of traumatic experiences

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A separate set of enzymes and transporters also plays a buffering role by eliminating acetyl-CoA from inside mitochondria created by the pyruvate dehydrogenase complex that is in excess of its utilization by the Krebs cycle