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Estrogen receptor upregulates CCL2 via NF-B signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis

Potential Side Effects: Gastrointestinal effects (most common): nausea, vomiting, diarrhea, constipation, abdominal paintypically mild to moderate and decreasing with gradual dose escalation [1] [3]

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