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Found in every cell of the body, it plays a crucial role in detoxification, immune defense, and cellular repair

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This initial phosphorylation cascade leads to autophosphorylation of the carboxy-terminal bidentate substrate-binding site (Tyr1349 and Tyr1356) of the c-Met and these residues have been shown as docking sites for downstream signaling molecules [52]

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For mKate reporter construction, the mKate2 gene was amplified from pRN10 (Addgene, plasmid 84454) 69 using a specific primer pair (Supplementary Table 3) and Q5 High-Fidelity DNA Polymerase (New England Biolabs)

By the way, this article has more information about the different forms of glutathione, if you're interested in learning more about that and which one to use