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If we remember to apply one, it can be uncomfortable to keep on for long periods

Moreover, ferroptosis, which occurs in tumor cells, can spread to neighboring cells via the paracrine release of lipid peroxides (Nishizawa 2021)

However, a potential drawback is that KD is typically low in dietary Trp [178], the precursor of several neuroprotective AhR ligands and serotonin pathway metabolites

Iron exchange in the mitochondria is mediated by DMT-1 and classical mitoferrins (Mfrn) 1 and 2 [38], which are incorporated into the electron transport chain and produce ATP under the stimulation of glucose

A primary concern is the scarcity of comprehensive in vivo studies and clinical trials

In vivo antitumor assay All animal operations followed the guidelines of the Institutional Animal Care and Use Committee (IACUC) of the Animal Experiment Center of the Chinese University of Hong Kong (Shenzhen, China, protocol number, CUHKSZ-AE2022004)