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The central structural feature of Sulbutiamine is the SS (disulfide) bond connecting two thiamine-derived fragments

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This disrupts the ionic balance inside and outside the cell, increases membrane permeability, impairs the exchange of substances across the membrane, and ultimately leads to the death of tumor cells

The addition of MOTS-c activated the Akt pathway in mouse skeletal muscle, which further positively regulated the expression of MOTS-c

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The neuropsychology of Huntingtons disease