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No finalized large-scale human clinical trials are published that demonstrate safety and efficacy in humans

Although reactive electrophiles such as chloroacetamides are generally considered to be promiscuous in target binding, we demonstrated here using a BODIPY-labelled analogue that the chloroacetamide-based GSTO1 inhibitor C1-27 exhibited a low degree of nonspecific reactivity

All the above methods have been systematically validated

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Annual meeting, Institute of Food Technologists 1014 June 2000

Effect of Human Glutathione S-Transferase hGSTP1-1 Polymorphism on the Detoxification of Reactive Metabolites of Clozapine, Diclofenac and Acetaminophen. Toxicology Letters, vol