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Lambs and kids: 1.5 -2.5 ml

NOX inhibition targets NADPH oxidases at the plasma membrane and within organelles: using selective NOX1/4 blockers or broader pan-NOX agents can dampen site-specific ROS generation, which in turn may slow fibrotic remodeling, protect endothelial function and vascular tone, and ease downstream metabolic stress

Once in solution, the peptide is no longer protected by the lyophilized matrix and becomes vulnerable to enzymatic degradation, oxidation, and thermal denaturation

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The majority of available evidence is derived from preclinical studies, while well-designed, long-term randomized clinical trials remain limited