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*Correspondence: Jing-Hua Yang, [email protected] ORCID: Kun Liu, orcid.org/0000-0002-9215-1572 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Although chemotherapy may induce CIPN via various pathways, the main characteristics are inflammation and neuronal necrosis