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Thus, VIC has been shown to have an extremely good antioxidant effect, protecting against oxidative stress, facilitating collagen synthesis, supporting skin health, enhancing immune function, improving wound-healing, and promoting iron absorption in the intestine

doi: 10.1007/s00394-013-0516-8 84

doi: 10.1093/humrep/deae107

Loss of PMK-1 (transcription factor of p38 MAPK) compromises the extended lifespan of daf-2(e1370) (insulin/insulin-like growth factor (IGF) receptor longevity mutant) 45

In the first two studies, changes in redox and methylation metabolism were reported but because the studies were open-label the changes in these biomarkers were not compared to a placebo group