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Singh M

doi: 10.4161/cc.8.23.10238 29 FuYLiuSYinSNiuWXiongWTanMet al

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The lack of a hook effect in degradation assays was particularly apparent in the presence of CRBN overexpression, where ( S )-dHTC1 induces maximal degradation at concentrations spanning more than 3 orders of magnitude (Extended Data Fig