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Similarly, cyclic hydrostatic pressure enhances the chondrogenic differentiation of BMSCs (Ogawa et al., 2009) in a dose- and time-dependent manner, and shows synergistic effects when co-cultured with nucleus pulposus cells ( In contrast, static loading generally produces negative effects

Best practices usually include: Start with the lowest dose in the dosage range

Challenges of Cholangiocarcinoma Detection in Patients with Primary Sclerosing Cholangitis

In presynaptic terminals, the exocytosis of neurotransmitters is triggered by the influx of calcium (Neher and Sakaba, 2008)

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Clinical trials of fresolimumab, an anti-TGF- monoclonal antibody that targets all three TGF- isoforms, show promise in reducing myofibroblast infiltration and fibrosis and is more well tolerated than many other anti-TGF- therapies [75]