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On the other hand, spontaneous and often substantial functional improvements [5355] after partial lesioning of the spinal cord are associated with the spontaneous sprouting of axons in the corticospinal tract [5658] and the formation of neural circuits by spared spinal cord tissue [26]

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Consistently, the risk of bias assessment, revealed a moderate risk for the first 6 studies scoring three points, and high risk for the 4 studies scoring five points