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For instance, Sheiha et al

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GPX4 upregulation in response to BRAFi EGFRi therapy blocks therapy-induced ferroptosis and drives resistance

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Because L-Citrulline largely bypasses first-pass liver metabolism, it raises plasma L-Arginine levels more efficiently than direct L-Arginine supplementation, gram for gram - a pharmacokinetic advantage that's driven by growing research interest in this amino acid specifically

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