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GSH depletion by BSO treatment inhibits L2/vDNA trafficking from the Golgi to the mitotic chromosomes, resulting in accumulation of L2/vDNA within the Golgi of infected cells, low levels of nuclear L2/vDNA, and inefficient infection

Extensive evidence has validated the concept of mechanism-based stratification and highlighted the need for personalized interventions tailored to individual molecular and neurobiological profiles (143-145)

But who stands to gain the most

Xenobiotica 9-10:10731081 Hayes JD, Flanagan JU, Jowsey IR (2005) Glutathione transferases

& Rafieian-Kopaei, M

This plurality complicates efforts to define, delimit, and manage coastal territories, which are intrinsically fluid and dynamic